fragment Fab
- Domaines
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- médecineallergologie
- biologieimmunologie
Terme :
- fragment Fab n. m.
Traductions
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anglais
Auteur : Labastrou, Éliane,Définition
A fragment of the immunoglobulin molecule obtained following papain hydrolysis of the molecule. The Fab moiety has an approximate molecular mass of 45 000 daltons and consists of one light chain linked to the N-terminal portion of the continuous heavy chain. Two Fab fragments are obtained from the hydrolysis of one 7 S immunogobulin and each fragment contains one antibody combining site.
Terme :
- Fab fragment