hypogammaglobulinémie à expression variable

Traductions

• anglais

  Auteur : Labastrou, Éliane, 1992

  Définition

  A heterogeneous group of disorders characterized by hypogamma-globulinemia, decreased antibody production in response to antigenic challenge, and recurrent pyogenic infections, and often associated with hematologic and autoimmune disorders. Most patients have normal numbers of circulating B cells but lack plasma cells, and are thus thought to have an intrinsic defect of B cell differentiation. Many also have T cell defects and exhibit cutaneous energy to recall antigens.

  Termes :

  1. common variable immunodeficiency
  2. common variable unclassifiable immunodeficiency
  3. acquired agammaglobulinemia
  4. common variable agammaglobulinemia
  5. common variable hypogammaglobulinemia