interleukine 1

Domaines: médecineallergologie

biologieimmunologie
Auteur: Labastrou, Éliane, 1992

Définition :

[...] cytokine agissant sur les stades les plus immatures des progéniteurs hématopoïétiques [...] en les sensibilisant aux autres CSF.

Note :

On distingue 1'IL‑1a et l'IL‑1ß, toutes les deux de 17kDa.

Termes :

interleukine 1 n. f.
IL-1 n. f.
facteur d'activation des lymphocytes n. m.
facteur d'activation lymphocytaire n. m.

Traductions

anglais
Auteur : Labastrou, Éliane, 1992
Définition

A macrophage-produced interleukin that induces the production of interleukin-2 by T cells that have been stimulated by antigen or mitogen; at least two types exist, designated α and ß. IL-1 or a similar protein is also produced by epithelial cells and stimulates fibroblast proliferation and release of proteolytic enzymes (e.g., collagenase) and prostaglandins in inflammatory processes. IL-1 also appears to be identical to endogenous pyrogen.

Termes :
1. interleukin-1
2. IL-1
3. lymphocyte-activating factor
[lymphocyte-activating factor] older term